Begin early at Old Town Square to beat crowds at the Astronomical Clock, then visit the Jewish Museum's Pinkas Synagogue. Lunch at a hidden courtyard café, explore the medieval streets and Charles Bridge on foot. Finish with evening drinks at a local wine bar near the Estates Theatre where Mozart premiered Don Giovanni.

Morning at DOX Contemporary Art Centre, Holesovice Market, lunch at a local restaurant, Letna beer garden for the Prague panorama at sunset.

Start at the Vojan Gardens for morning calm, walk to the Mala Strana Library café for coffee, explore Functionalist architecture on Nádražní Street, lunch at a traditional hospoda, then spend afternoon in the Fuks Gallery or Bet Tikvah Synagogue. End with sunset drinks at a wine bar overlooking the Vltava.

Start at Žižkov Television Tower for panoramic city views and its quirky interior design museum. Wander through Vinohrady's gallery-lined streets (adjacent, walkable), then lunch at a local hospoda. Afternoon: explore the Jewish Cemetery and nearby Vinohrady Cemetery. Evening: catch theatre at Divadlo na Zábradlí or live music at a small venue on Bořivojova, then dinner at a traditional Czech wine bar.

Start at Náměstí Jiřího z Poděbrad with coffee at a corner café, then walk Slavíkova Street admiring Art Nouveau details. Mid-morning, visit the Vinohrady Theatre or a small gallery like Futura. Lunch at a neighbourhood bistro, afternoon exploring the residential backstreets toward Riegrovy sady park. Evening drink at an intimate wine bar before dinner.

Start at St. Nicholas Church at dawn to avoid crowds, then explore the Jewish Museum's four sites scattered across the neighbourhood. Lunch at a hidden courtyard restaurant near Petřín Park, spend afternoon climbing to Petřín Lookout Tower for city views and gardens, finish with evening drinks in a baroque cellar bar on Maltézské náměstí.